Chinese Version

Professor at Department of Materials Science and Engineering

zhengyudong@mater.ustb.edu.cn

+86-010-62330802

Main Building, Room 417

Biography

From 1993 to 2004, I worked in Institute of Functional Material, South China University of Technology, majoring in research on biomedical polymer and composite materials, tissue engineering scaffold materials and cartilage repair. I undertook and participated in several projects such as Natural Science Foundation of China, Science-Technology Project of Guangdong Province and National High-Tech Research and Development Project, mainly on the preparation and modification of PHBV hydrogel materials as well as tissue engineered cartilage culture. The related research results were published in academic journals of biological materials such as JBMR, obtained a number of national invention patents.

Since 2004, I have been working in School of Material Science and Engineering, University of Science and Technology Beijing. I built Research Center of Biomedical Materials, mainly carrying out research on preparation and characterization of biomedical hydrogel implant materials, biocompatible conductive hydrogels and nanocomposite biomaterials, as well as their applications in biomedical field and tissue regeneration, such as skin, cartilage and neural restoration. In 2011 and 2013, I went to Britain for exchange visits and cooperation of the international projects. I am also communicating with various internal and global groups on biomaterial and medicine. As project leader, I directed and completed five projects from Natural Science Foundation of China and The Royal Society-NSFC international joint project grant. I undertook and completed several projects from National Basic Research Program of China (973 Program), National High-Tech Research and Development Project (863 Program), The National Science and Technology Support Project of China, Beijing Municipal Science and Technology Plan Projects and Industrial Development Projects. A series of research achievements have been achieved on composite biomaterials, nanocomposite hydrogels, modification of nano bacterial cellulose, as well as their applications on regeneration of skin, cartilage and nerve, winning the scientific research national and provincial-level incentives awards. I have published many papers in Biomaterials, Acta biomaterials, J of Materials chemistry, J Control release, Biomedical Materials, Tissue Engineering and many other top journals of biomaterials. 17 national invention patents have been obtained. Among which the modified nano bacterial cellulose multifunctional wound dressing and microcapsule for self-repair of composites have been successfully transformed to industrial development.  One of the products obtained national registration certificates of medical apparatus and instruments. I have guided more than 30 PhD students and graduate students on the field of biological materials. The biological composite research projects and achievements conducted by undergraduates and graduate students who I guided have won incentives of scientific and technical innovation competition at national and provincial levels several times.

At present, I am council member of Chinese Society of Biomaterials, the fifth committee member of Chinese Society of Biomedical Engineering-Biological Material Branch, council member of Chinese Society for Composite Materials, member of International Society for Biomaterial and so on. In addition, I have acted as symposium chair and given special invited reports for the branches on the international conferences on biomaterials, such as Chinese Society of Biomedical Engineering-Biological Material Branch National Congress, Chinese Society for Multiple Materials-Biological Material Branch Conference, International Conference on Composite Materials, Conference on Tissue Engineering and Regenerative Medicine, and other domestic and international academic meetings for many times.

Research Interests

1.Graft or link of bioactive molecule to biopolymer, or fabrication and modification of nature and synthetic biodegradable and biological polymer used for tissue engineering scaffold, drug release carrier ; 

2.Preparation and Self-assembly of bioactive hydrogels and namo-hybrid conductive hydrogels made from nature bioactive micromolecules ,hydrophilic polymer, compound with nano carbon,nano bioactive particles,nano-silver, et,al, used for bone/ cartilage/ Skin/nerve regeneration and repair.

3.The interaction of biomaterial  to cell, , DNA with physical and chemical changes  in physiological condition;

4.Exploration, characterization of the response of protein, cell and tissue to intelligent composite hydrogels, with biologic signal change including PH value, temperature, electrical signal and biomechanical envionment et al; 

5.Biocompatible electrichemical active biocomposites used for implantable battery.

Active Research Projects

1.Natural Science Foundation of China, Laminated Mesoporous Conductive Gel Multi-selective Redox System and Energy Conversion Device Prototype(No 51473019), 2015-2018, （Project Leader） 

2.Natural Science Foundation of China, The Force-Electric Coupling of Ordered Array Nano-Hydrogel Driving by the Alternating Field and Used for Cell Regulation(No 51273021),2012-2015,（Project Leader ）

3.Natural Science Foundation of China, Oriented Structure of Continnuous Phase Conductive Hydrogels and their Bioelectricity Respond (No51073024), 2011-2013（Project Leader）

4.Natural Science Foundation of China, Preparation, Characteristic and Deformation Mechanism of Biofunctional Auxetic Hydrogels(No51073024)  2008-2010 (Project  Leader)

5.The National Science and Technology Support Project of China(Grant No. 2011BAK15B04). The biological safety evaluation for Carbon nano materials   2011-2015 （Subproject Leader）

6.The National Science and Technology Support Project of China, Biological Evaluationand the technical specification of Contraception intrauterine device 2006-2009（Subproject Leader）

7.The Royal Society-NSFC international joint project grant (No. 5111130207),The self-assemblage of tropism structural conductive nanofibre/hydrogels and the response to bio-electricity 2011-2013年（Project Leader ）

8.Beijing Municipal Science and Technology Plan Projects (No. Z111103066611005), Research and Development of  Nano Bacterial Cellulose mulfunctional Wound Dressing 2011-2012 (Project  Leader)

9.Pre-Research Project of Astronautics Ministry,Preparation of Biolayer Microcapsule for Self-repair of Composites, 2010-2012(Project Leader)

10.Pre-Research Project of Astronautics Ministry, Controlled Release Microcapsule Curing Agent and Curing Properties Measurement 2013-1015 (Project Leader)

11.Industrial Development Projects,Research and Measurement of Bio-base Materials for Biomedical Application ，2014-2015 (Project Leader)

12.Industrial Development Projects, Skin Repair Materials Based on Functional nano-cellulose ，2013-2015 (Project Leader)

13.Industrial Development Projects, Artificial Tissue Engineering Meniscus ，2010-2013 (Project Leader)

14.Industrial Development Projects,  TheSurface Modification and Development of long-action antibacterial Stainness Steel，2009-2012 (Project Leader)

15.Natural Science Foundation of Guangdong Province,The Synthetic,Structure and Properties of Micrpbial Polyester, 1995-1997 (Project Leader)

16.Natural Science Foundation of Guangdong Province, The synthetic of Polyhydroxyalkylesters by Activated sludge process methods , 1997-1999 (Project Leader)

17.“十五”Major Science and Technology Project, Compound Polyhydroxyalkylesters/sol-gel Bioglass Bone and Cartilage Tissue Engineering, 2000-2003 (Project Leader)

18.High-Tech Development Project of China, Bioactive artificial Bone Materials for Bone Repair, 2000-2005 (Participants)

Published Research (English Only)

1.pH-and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery;Shi X, Zheng Y, Wang G, Lin Q, Fan J;RSC Advances, 2014.9 4(87): 47056-47065.(IF:3.708)

2.Protein Adsorption Behaviors of Carboxymethylated Bacterial Cellulose Membranes; Lin Q, Zheng Y, Wang G., Shi X, Zhang T, Yu J, Sun J.International journal of biological macromolecules, 2014.11 73:264-269.(IF:3.096)

3.Cauda Equina-Derived Extracellular Matrix for Fabrication of Nanostructured Hybrid Scaffolds Applied to Neural Tissue Engineering，Xiaoxiao Wen,   Yu Wang,   Zhiyuan Guo,   Haoye Meng,  Jingxiang Huang,  Li Zhang,   Bin Zhao,   Qing Zhao,  Yudong Zheng,    Jiang Peng,  TISSUE ENGINEERING: Part A Volume 21, Numbers 5 and 6, 2014.11（1095-1105）(IF:4.448)

4.In vitro and in vivo investigation of bacterial cellulose dressing containing uniform silver sulfadiazine nanoparticles for burn wound healing. Wen X, Zheng Y, Wu J, Yue L, Wang C, Luan J, Wu Z, Wang K. Progress in Natural Science: Materials International, 2015.4 25(3), 197-203.(IF:1.837)

5.Multifunctional MgF2/Polydopamine Coating on Mg Alloy for Vascular Stent Application. Liu X, Zhen Z, Liu J, Xi T, Zheng Y, Guan S, Zheng Y F, Cheng Y. Journal of Materials Science & Technology. 2015.3 31:733-743. (IF:1.909)

6.Synthesis of bio-castor oil polyurethane flexible foams and the influence of biotic component on their performance. Wang C, Zheng Y, Xie Y, Qiao K, Sun Y, Yue L. Journal of Polymer Research. 2015.7 22(8), 1-9. (IF:1.920)

7.Hydrophilic nanofiber of bacterial cellulose guided the changes in the micro-structure and mechanical properties of nf-BC/PVA composites hydrogels. Qiao K, Zheng Y, Guo S, Tan J, Chen X, Li J, Xu D, Wang J. Composites Science and Technology. 2015.8 118, 47-54. (IF:3.569)

8.An environmentally friendly preparation and characterization of waterborne polyurethane hydrogels by polyvinyl alcohol physical cross-linking to improve water absorption. Wang C, Zheng Y, Qiao K, Xie Y, Zhou X. RSC Advances. 2015.8 5(90): 73882-73891. (IF:3.708)

9.Immobilization of collagen peptide on dialdehyde bacterial cellulose nanofibers via covalent bonds for tissue engineering and regeneration. Wen X, Zheng Y, Wu J, Wang L. N, Yuan Z, Peng J, Meng H. International journal of nanomedicine. 2015.7 10: 4623-4636. (IF:4.383)

10.Bacterial cellulose membrane supported three-dimensionally dispersed silver nanoparticles used as membrane electrode for oxygen reduction reaction in phosphate buffered saline，Tao Zhang, Yudong Zheng, Shumin Liu, Lina Yue, Yao Gao, Yi Yao，Journal of Electroanalytical Chemistry 2015.5 750 (2015) 43-48.(IF:2.729)

11.Electrospun bro-porous polyurethane coatings for implantable glucose biosensors，Ning Wang, Krishna Burugapalli ,Wenhui Song， Justin Halls ， Francis Moussy ， Asim Ray ，Yudong Zheng， Biomaterials,  34:888-901, 2013（IF 7.604)

12.The preparation and characterization of double-layer microcapsules used for the self-healing of composites, Ru Tian, Xiaoli Fu, Yudong Zheng*,  Xin Liang,  Qiaoli Wang, Ying Ling, Baoshun Hou Journal of Materials Chemistry, 22:25437–25446,2012 (IF 6.101)

13.In situ synthesis of silver-nanoparticles/bacterial cellulose compositesfor slow-released antimicrobial wound dressing，Jian Wu, Yudong Zhenga,∗, Wenhui Songb, Jiabin Luan ,  Qi Wang  , Shaolin Guo,  Carbohydrate Polymers 102 (2014) 762– 771，（IF 3.942）

14.The characterization of the concentration of the single-walled carbon nanotubes in aqueous dispersion by UV-Vis-NIR   spectroscopy ，Bing Yang, Lingling Ren, Luming Li,Xingfu Tao, Yunhua Shi，Yudong Zheng，Analyst，138：6671–6676,2013 (IF 3.969)

15.Nanotubular surface modification of metallic implants via electrochemical anodization technique,Luning Wang,Min Jin, Yudong Zheng,Yueping Guan,Xin Lu,Jingli Luo, International Journal of Nanomedicine 01/2014; 9:4421-4435 (IF 4.2)

16.Effect of selective oxidation of bacterial cellulose on degradability in phosphate buffer solution and their affinity for epidermal cell attachment;Shi X, Cui Q, Yudong Zheng *, Peng S, Wang G, Xie Y;RSC Advances, 2014, 4(105): 60749-60756.(IF:3.708)

17.pH-and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery;Shi X, Zheng Y*, Wang G, Lin Q, Fan J;RSC Advances, 2014, 4(87): 47056-47065.(IF:3.708)

18.Tailored fibro-porous structure of electrospunpolyurethane membranes, the i size-dependent properties and trans-membrane glucose diffusion ,  Ning Wang, Krishna Burugapalli , WenhuiSong , JustinHalls , FrancisMoussy, Yudong Zheng  YanxuanMa, ZhentaoWu, KangLi, Journal of Membrane Science 427 :207–217,2013 (IF 4.093)

19.Electrospun polyurethane-core and gelatin-shell coaxial fibre coatings forminiature implantable biosensors，Ning Wang, Krishna Burugapalli, Shavini Wijesur,Mahshid Yazdi Far, Wenhui Song, Francis Moussy, Yudong Zheng, Yanxuan Ma, Zhentao Wu，Kang Li， Biofabrication，6：015002 (18pp) doi:10.1088/1758-5082/6/1/015002，2014(IF 3.705)

20.Selective oxidation of bacterial cellulose by NO2/HNO3，Qiuyan Cui,Yudong Zheng*,Qinghua Lin,Wenhui Song, Kun Qiao,Shumin Liu ，RSC Advances, 4: 1630-1639, 2014(IF3.708)

21.Influence of dialdehydebacterial cellulose with the nonlinear elasticity and topology structure of ECM on cell adhesion and proliferation， Jian Wu， Yudong Zheng*，Zhou Yang，Qinghua Lin，Kun Qiao、Xiaohua Chen，Pen Yang，RSC Advances, 4 ：3998-4009, 2014（IF3.708）

22.Low swelling hyperbranched poly(amine-ester) hydrogels for pH-modulated differential release of anticancer drugs，Hongbin Zhang, Yourui Dong, Lei Wang, Guojie Wang,Jian Wu, Yudong Zheng, Huai Yang  Siquan Zhu， J. Mater. Chem., , 21：13530–13537，2011 (IF 6.101)

23.Thiol/Acrylate-Modified PEO-PPO-PEO Triblocks Used as Reactive and Thermosensitive Copolymers，Guoguang Niu, Hongbin Zhang, Li Song, Xiaopeng Cui, Hui Cao, Yudong Zheng, Siquan Zhu, Zhou Yang,  Huai Yang，Biomacromolecules 2008, 9, 2621–2628（IF5.788）

24.Synthesis and characterization of acrylamide/N-vinylpyrrolidone copolymer with pendent thiol groups for ophthalmic applications Guoguang Niu a, Ying Yang c, Hongbin Zhang a, Jun Yang c, Li Song a, Miki Kashima a, Zhou Yang a, Hui Cao , Yudong Zheng , etal, Acta Biomaterialia 2009，5（4）：1056~1063（ IF5.684）

25.Synthesis and characterization of reactive poloxamer 407s for biomedical applications，Guoguang Niu   Fengyi Du  , Li Song  , Hongbin Zhang   Jun Yang  , Hui Cao   Yudong Zheng  , Zhou Yang a,Guojie Wang  , Huai Yang  ,  Siquan Zhu  Journal of Controlled Release 138 (2009) 49–56,(IF 7.261)

26.Photoswitched Protein Adsorption on Electrostatically Self-Assembled Azobenzene Films Jian Zhang, Te Hu, Yibiao Liu, Yanxuan Ma, Jie Dong,  Liping Xu,   Yudong Zheng,  Huai Yang,   Guojie Wang，  ChemPhysChem ,Volume 13, Issue 11,  2671–2675, August 6, 2012 (IF3.36)

27.Protein Adsorption Behaviors of Carboxymethylated Bacterial Cellulose Membranes;Lin Q, Zheng Y*, Wang G., Shi X, Zhang T, Yu J, Sun J.International journal of biological macromolecules, 73(2015) 264-269.(IF:3.096)

28.Nanoparticle assembly of a photo- and pH-responsive randomazobenzene copolymer，Ning Feng, Guoxiang Han, Jie Dong, Hao Wu, Yudong Zheng, Guojie Wang，Journal of Colloid and Interface Science， 421 (2014) 15–21（IF 3.135）

29.Heterogeneous PVAhydrogel swithmicro-cellsofboth positive and negative Poisson’sratios ，Yanxuan Ma, Yudong Zheng* Haoye Meng, Wenhui Song, Xuefeng Yao, Hexiang Lv ，J of the mechanical behavior of biomedical materials,Mar   23:22-31, 2013 (IF 2.368)

30.Silver nanoparticle/bacterial cellulose gel membranes for antibacterial wound dressing: investigation in vitro and in vivo，Jian Wu, Yudong Zheng*, Xiaoxiao Wen, Qinghua Lin, Xiaohua Chen，  Zhigu Wu， Biomed. Mater. ,9 (2014) 035005 (12pp) (IF 2.922)

31.Concentration-dependent cytotoxicity of copper ions on mouse fibroblasts in vitro: effects of copper ion release from TCu380Avs TCu220C intra-uterine devices, Bianmei Cao，Yudong Zheng*  Tingfei Xi  Chuanchuan Zhang  Wenhui Song  Krishna Burugapalli  Huai Yang，Yanxuan Ma，Biomed Microdevices 14:709–720,2012 (IF 2.765)

32.Impregnation of silver sulfadiazine into bacterial cellulose for antimicrobial and biocompatible wound dressing ，Jiabin Luan , Jian Wu  Yudong Zheng* , Wenhui Song , Guojie Wang , Jia Guo  Xun Ding ，  Biomed. Mater. 7:065006 (11) Nov 2012 , (IF2.158) 

33.Poly(vinyl pyrrolidone) wrapped multi-walled carbon nanotube/poly(vinyl alcohol)composite hydrogels，Yanyi Huang , Yudong Zheng* , Wenhui Song , Yanxuan Ma, Jian Wu, Lizhen Fan， Composites: Part A 42 ：1398–1405，2011 (IF 2.744)

34.Improvement in hydrophilicity of PHBV films by plasma treatment ，Yingjun Wang, Ling Lu, Yudong Zheng, Xiaofeng Chen，Journal of Biomedical Materials Research Part A，2006， 76， 589-595,(IF 2.841)

35.Characteristic Comparison of Bioactive Scaffolds Based on Polyhydroxyalkoanate /bioceramic hybrids，Yudong Zheng*，Yingjun Wang，Huai Yang, XiaofenChen，Zhonghua Chen, Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 80B, Issue 1, 2007. Pages 236-243 (IF2.328)

36.Performance of novel bioactive hybrid hydrogels in vitro and in vivo used for artificial cartilage，Yudong Zheng*, Hexiang Lv, Yingjun Wang, Huading Lu, LiuQing，Tingfei Xi，Biomed. Mater. ，2009，4 ：7-13(IF2.922)

37.Mineralization behavior and interface properties of BG-PVA/bone composite implants in simulated body fluid，Yanxuan Ma , Yudong Zheng* , Xiaoshan Huang , Tingfei Xi ,Xiaodan Lin , Dongfei Han，Wenhui Song， Biomed. Mater. 5 (2010) 025003 :1~8,(IF2.922)

38.Preparation and characterization of bioglass/polyvinyl alcohol composite hydrogel，Hong Xu, Yingjun Wang, Yudong Zheng, Xiaofeng Chen, et al,  Biomed. Mater, 2007,2 ,62–66(IF2.922)

39.Release behavior of cupric ions forTCu380A and TCu220C IUDs Bianmei Cao, Tingfei Xi and Yudong Zheng, Biomed. Mater. 3 (2008) 044114 1~7 (IF2.922)

40.In vitro Cytotoxicity of Bacterial Cellulose Scaffold for Tissue Engineered Bone . Chen Y M, Tingfei Xi, Yudong Zheng, Tingting Guo, Jiaquan Hou, Yizao Wan, Chuan Gao. Journal of Bioactive and Compatible Polymers, 2009, 24: 137-145.(IF2.5)